HDAC8 抗体 (AA 50-150)
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北京 101111
Quick Overview for HDAC8 抗体 (AA 50-150) (ABIN6943610)
抗原
See all HDAC8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-150
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原理
- HDAC8 (2T1) Monoclonal Antibody
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant human HDAC8 between 50 to 150 amino acids
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亚型
- IgG
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应用备注
- WB(1:300-5000), FCM(1:20-100)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- HDAC8 (Histone Deacetylase 8 (HDAC8))
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别名
- HDAC8
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背景
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Synonyms: Histone deacetylase 8, HD8, HDAC8
Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.
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基因ID
- 55869
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UniProt
- Q9BY41
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途径
- Cellular Glucan Metabolic Process
抗原
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