H2AFX 抗体 (AA 1-50)
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北京 101111
Quick Overview for H2AFX 抗体 (AA 1-50) (ABIN6943600)
抗原
See all H2AFX 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-50
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原理
- Histone H2AX (9C9) Monoclonal Antibody
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic peptide within human Histone H2A.X aa 1-50
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亚型
- IgG
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anti-H2A Histone Family, Member X (H2AFX) (AA 115-143), (C-Term) antibody
H2AFX 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 938CT5-1-1 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (C-Term) antibodyH2AFX 适用: 人, 小鼠 WB, IHC, ICC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (pSer140) antibodyH2AFX 适用: 人 WB, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (AA 115-143), (C-Term) antibodyH2AFX 适用: 人 WB, IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 8C5 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (H2A.XK119ub) antibodyH2AFX 适用: 人 WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibodyH2AFX 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (C-Term) antibodyH2AFX 适用: 人 WB, IF, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (AA 1-30), (N-Term) antibodyH2AFX 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 980CT1-5-5 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (H2A.XS139ph) antibodyH2AFX 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (H2AXS139ph) antibodyH2AFX 适用: 人 WB, ELISA, IF, ChIP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB(1:300-5000), IHC-P(1:200-400), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 12 months
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- H2AFX (H2A Histone Family, Member X (H2AFX))
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别名
- H2AFX
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背景
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Synonyms: Histone H2A.X, Histone H2AX, H2a/x, H2AX, H2AFX., H2A histone family member X.
Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
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基因ID
- 3014
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UniProt
- P16104
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途径
- Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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