CXCR7 抗体
Quick Overview for CXCR7 抗体 (ABIN6943568)
抗原
See all CXCR7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant human CXCR7 between 300 to 400 amino acids
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亚型
- IgG
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anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibody
KO Validated CXCR7 适用: 人 WB, ELISA, FACS, IF, IHC (p), IP, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibodyCXCR7 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (Internal Region) antibodyCXCR7 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 151-250) antibodyCXCR7 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 311-360) antibodyCXCR7 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (Extracellular Domain) antibodyCXCR7 适用: 人, 大鼠, 小鼠, 犬, Cow, Pig, 马, Bat, Hamster, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (Cytoplasmic Domain) antibodyCXCR7 适用: 人, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) antibodyCXCR7 适用: 人 FACS 宿主: 小鼠 Monoclonal 10D1-J16 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 50-150) antibodyCXCR7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 330-358), (C-Term) antibodyCXCR7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB23520 unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))
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别名
- GPCR RDC1
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背景
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Synonyms: Atypical chemokine receptor 3, C-X-C chemokine receptor type 7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, CXC-R7, CXCR-7, RDC-1, ACKR3
Background: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CXCL11 and CXCL12/SDF1. Chemokine binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization and activation of MAPK signaling pathway. Required for regulation of CXCR4 protein levels in migrating interneurons, thereby adapting their chemokine responsiveness. In glioma cells, transduces signals via MEK/ERK pathway, mediating resistance to apoptosis. Promotes cell growth and survival. Not involved in cell migration, adhesion or proliferation of normal hematopoietic progenitors but activated by CXCL11 in malignant hemapoietic cells, leading to phosphorylation of ERK1/2 (MAPK3/MAPK1) and enhanced cell adhesion and migration. Plays a regulatory role in CXCR4-mediated activation of cell surface integrins by CXCL12. Required for heart valve development. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates
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基因ID
- 57007
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UniProt
- P25106
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途径
- Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling
抗原
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