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Recombinant GLI3 抗体 (AA 1300-1600)

This 兔 单克隆 antibody specifically detects GLI3 in WB 和 IF (cc). It exhibits reactivity toward 人.
产品编号 ABIN6943536
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant GLI3 抗体 (AA 1300-1600) (ABIN6943536)

抗原

See all GLI3 抗体
GLI3 (GLI Family Zinc Finger 3 (GLI3))

抗体类型

Recombinant Antibody

适用

  • 61
  • 28
  • 20
  • 1
  • 1
  • 1
  • 1

宿主

  • 55
  • 5
  • 2

克隆类型

  • 40
  • 22
单克隆

标记

  • 29
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This GLI3 antibody is un-conjugated

应用范围

  • 32
  • 18
  • 18
  • 15
  • 14
  • 10
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1300-1600

    原理

    GLI3 Recombinant Antibody

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein within human Gli3 aa 1300-1600.

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), IF(ICC)(1:50-200)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    GLI3 (GLI Family Zinc Finger 3 (GLI3))

    别名

    GLI3

    背景

    Synonyms: Transcriptional activator GLI3, GLI3 form of 190 kDa, GLI3 full-length protein, Transcriptional repressor GLI3R, GLI3 C-terminally truncated form, GLI3 form of 83 kDa, GLI3-190, GLI3FL, GLI3-83,

    Background: Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repressor GLI3R, rather than the repressor gradient itself or the activator/repressor ratio gradient, specifies limb digit number and identity. In concert with TRPS1, plays a role in regulating the size of the zone of distal chondrocytes, in restricting the zone of PTHLH expression in distal cells and in activating chondrocyte proliferation. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.

    基因ID

    2737

    UniProt

    P10071

    途径

    Hedgehog Signaling
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