gamma Tubulin 抗体
Quick Overview for gamma Tubulin 抗体 (ABIN6943513)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein G.
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免疫原
- KLH conjugated synthetic peptide derived from human Gamma Tubulin
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亚型
- IgG
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anti-Tubulin, gamma (TUBG) (AA 351-451) antibody
TUBG 适用: 小鼠 IF (p), IF (cc), ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- gamma Tubulin (TUBG) (Tubulin, gamma (TUBG))
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别名
- Gamma Tubulin
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背景
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Synonyms: Centrosome Marker, Gamma 1 tubulin, gamma tubulin, gamma-tubulin, Gamma 2 tubulin, Gamma Tubulin 1, Gamma Tubulin 2, Gamma tubulin complex component 1, GCP 1, GCP-1, GCP1, MGC131994, TUBG, TUBG1, TUBG2, Tubulin gamma 1 chain, Tubulin gamma 2 chain, Xgam, TBG1_HUMAN, TBG2_HUMAN, Tubulin gamma-1 chain, Gamma-1-tubulin, Gamma-tubulin complex component 1.
Background: Centrosome Marker
Gamma tubulin, a member of the tubulin superfamily, is a ubiquitous and highly conserved protein within the microtubule organizing centre (MTOC). Gamma tubulin is not a component of microtubules, rather it functions as the microtubule nucleator at the MOTC, is responsible for binding microtubule minus ends and mediating the link between microtubles and the centrosome. By binding to the beta tubulin subunit of the tubulin molecule, it establishes the polarity of a microtubule leaving the alpha tubulin subunit exposed at the positive end.
The abundance of Gamma tubulin is less than 1 % of the level of either alpha or beta tubulin. It shares approximately 28-32 % identity with alpha tubulin from various organisms and 32-36 % identity with beta tubulins. The detection, localization and characterization of proteins involved in microtubule function is fundamental to the understanding of mitosis, meiosis and the microtubule cytoskeleton. -
基因ID
- 7283
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UniProt
- P23258
抗原
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