FOXA2 抗体
Quick Overview for FOXA2 抗体 (ABIN6943477)
抗原
See all FOXA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人
-
纯化方法
- Purified by Protein A.
-
免疫原
- Human FOXA2 between 350-450 amino acids
-
亚型
- IgG
-
-
anti-Forkhead Box A2 (FOXA2) (AA 363-457) antibody
FOXA2 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 7E6 unconjugated
anti-Forkhead Box A2 (FOXA2) (Middle Region) antibodyFOXA2 适用: 人, 小鼠, 大鼠, 犬, 兔, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (C-Term) antibodyVerified FOXA2 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 201-300) antibodyFOXA2 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 363-457) antibodyFOXA2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 363-457) antibodyFOXA2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 380-407) antibodyFOXA2 适用: 人, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) (AA 128-157) antibodyFOXA2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box A2 (FOXA2) antibodyFOXA2 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Forkhead Box A2 (FOXA2) antibodyFOXA2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 7H4B7 unconjugated
-
-
应用备注
-
WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- FOXA2 (Forkhead Box A2 (FOXA2))
-
别名
- FOXA2
-
背景
-
Synonyms: Hepatocyte nuclear factor 3-beta, Forkhead box protein A2, Transcription factor 3B, HNF-3-beta, HNF-3B, TCF-3B, FOXA2
Background: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs, FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis, regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
-
基因ID
- 3170
-
UniProt
- Q9Y261
-
途径
- Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
抗原
-
