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Recombinant DNMT3B 抗体 (C-Term)

The 兔 单克隆 anti-DNMT3B antibody (ABIN6943094) specifically detects DNMT3B in WB. The antibody is reactive with 人 samples.
产品编号 ABIN6943094
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
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Quick Overview for Recombinant DNMT3B 抗体 (C-Term) (ABIN6943094)

抗原

See all DNMT3B 抗体
DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This DNMT3B antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    Dnmt3b Recombinant Antibody

    预测反应

    Human,Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant human protein DUSP6 between 350 to C-terminus

    亚型

    IgG
  • 应用备注

    WB(1:300-5000)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

    别名

    Dnmt3b

    背景

    Synonyms: DNA (cytosine-5)-methyltransferase 3B, DNA methyltransferase HsaIIIB, Dnmt3b, DNA MTase HsaIIIB, M.HsaIIIB, DNMT3B

    Background: Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing (By similarity). In association with DNMT1 and via the recruitment of CTCFL/BORIS, involved in activation of BAG1 gene expression by modulating dimethylation of promoter histone H3 at H3K4 and H3K9. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Function as transcriptional corepressor by associating with ZHX1.

    基因ID

    1789

    UniProt

    Q9UBC3
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