COPS5 抗体
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- 抗原 See all COPS5 抗体
- COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This COPS5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human JAB1 aa 1-100
- 克隆位点
- 5H4
- 亚型
- IgG
- Top Product
- Discover our top product COPS5 Primary Antibody
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anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) antibody
COPS5 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (AA 1-334) antibodyCOPS5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) antibodyCOPS5 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) antibodyCOPS5 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (Internal Region) antibodyCOPS5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (AA 8-334) antibodyCOPS5 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) antibodyCOPS5 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (N-Term) antibodyCOPS5 适用: 人, 小鼠, 大鼠, Pig, 马, 兔, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (Internal Region) antibodyCOPS5 适用: 人 WB, IHC, IHC (p), IP 宿主: 小鼠 Monoclonal unconjugated
anti-COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (AA 221-334) antibodyCOPS5 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))
- 别名
- COPS5 (COPS5 产品)
- 别名
- BcDNA.LD14392 antibody, BcDNA:LD14392 antibody, CG14884 antibody, CH5 antibody, CSN-5 antibody, Csn5 antibody, DCH5 antibody, Dch5 antibody, Dmel\\CG14884 antibody, JAB1 antibody, JAB1/CSN5 antibody, Jab1 antibody, JadBp antibody, csn5 antibody, dch5 antibody, jab1/csn5 antibody, l(3)89Cf antibody, l(3)L4032 antibody, l(3)M203 antibody, quo antibody, COPS5 antibody, MGC76063 antibody, AI303502 antibody, CSN5 antibody, Mov34 antibody, Sgn5 antibody, zgc:73130 antibody, MOV-34 antibody, SGN5 antibody, COP9 signalosome subunit 5 antibody, COP9 signalosome complex subunit 5 antibody, COP9 signalosome subunit 5 S homeolog antibody, CSN5 antibody, COPS5 antibody, cops5 antibody, CpipJ_CPIJ012314 antibody, Bm1_46585 antibody, VDBG_06932 antibody, LOAG_01443 antibody, csn5 antibody, Cops5 antibody, cops5.S antibody, csn-5 antibody
- 背景
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Synonyms: COP9 signalosome complex subunit 5, Jun activation domain-binding protein 1, SGN5, Signalosome subunit 5, COPS5, CSN5, JAB1
Background: Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity by itself and requires the other subunits of the CSN complex. Interacts directly with a large number of proteins that are regulated by the CSN complex, confirming a key role in the complex. Promotes the proteasomal degradation of BRSK2.
- 基因ID
- 10987
- UniProt
- Q92905
- 途径
- Cell Division Cycle
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