CMA1 抗体
Quick Overview for CMA1 抗体 (ABIN6942587)
抗原
See all CMA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human Mast Cell Chymase aa 50-200
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亚型
- IgG
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anti-Chymase 1, Mast Cell (CMA1) (Internal Region) antibody
Verified CMA1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) antibodyCMA1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (C-Term) antibodyCMA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-247) antibodyCMA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 9-247) antibodyCMA1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 1-247) antibodyCMA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-247) antibodyCMA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-197) antibodyCMA1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 84-118) antibodyCMA1 适用: 人 WB 宿主: 兔 Polyclonal RB53046 unconjugated
anti-Chymase 1, Mast Cell (CMA1) antibodyCMA1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 12 months
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- CMA1 (Chymase 1, Mast Cell (CMA1))
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别名
- CMA1
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背景
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Synonyms: Chymase 1, Alpha-chymase, Mast cell protease I, CMA1, CYH, CYM.
Background: Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Mast Cell Chymase, also known as CMA1 or MCT1, is a major secreted serine protease that is involved in vasoactive peptide generation, extracellular matrix degradation and regulation of gland secretion. The human chymase gene, which maps to human chromosome 14q11.2, encodes a preproenzyme with a 19 amino acid signal peptide, an acidic 2 amino acid propeptide and a 226 amino acid catalytic domain. Mast Cell Chymase is a chymotryptic serine proteinase which is a member of the peptidase family S1. Expressed in mast cells, Mast Cell Chymase is associated with the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. Mast cell proteases are a family of rodent protein homologs to human tryptases that are specifically expressed in mast cells and may serve as highly specific markers in the analysis of mast cell heterogeneity, differentiation and function.
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基因ID
- 1215
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UniProt
- P23946
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
抗原
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