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CD46 抗体

This 兔 单克隆 antibody specifically detects CD46 in WB, IHC (p), IF (p) 和 IF (cc). It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN6942441
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD46 抗体 (ABIN6942441)

抗原

See all CD46 抗体
CD46

适用

  • 141
  • 34
  • 19
  • 11
  • 10
  • 3
人, 大鼠

宿主

  • 90
  • 68
  • 2
  • 2

克隆类型

  • 93
  • 69
单克隆

标记

  • 60
  • 16
  • 14
  • 10
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CD46 antibody is un-conjugated

应用范围

  • 93
  • 89
  • 50
  • 42
  • 36
  • 28
  • 18
  • 14
  • 13
  • 9
  • 7
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

4C3
  • 交叉反应

    人, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic peptide within human CD46 aa 50-100

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    CD46

    别名

    CD46

    背景

    Synonyms: Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen, CD46, MCP, MIC10, AHUS2,

    Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.

    基因ID

    4179

    UniProt

    P15529

    途径

    Regulation of Actin Filament Polymerization
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