CD11b 抗体
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北京 101111
Quick Overview for CD11b 抗体 (ABIN6942386)
抗原
See all CD11b (ITGAM) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD11b Monoclonal Antibody
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant Human ITGAM
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亚型
- IgG
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应用备注
- WB(WB(1:1000-2000)), IHC-P(IHC-P(1:200-800)), IHC-F(IHC-F(1:200-800)), IF(IHC-P)(IF(IHC-P)(1:200-800))
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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别名
- CD11b
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背景
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Synonyms: Antigen CD11b (p170), CD11 antigen like family member B, CD11 antigen like family member C, Cell surface glycoprotein MAC 1 subunit alpha, CR 3 alpha chain, CR3A, Integrin alpha M, Integrin alpha X, Integrin, alpha M (complement component 3 receptor 3 subunit), Integrin, alpha X (antigen CD11C (p150), alpha polypeptide), Integrin, alpha X (complement component 3 receptor 4 subunit), ITGAM, ITGAX, Leu M5, alpha subunit, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor MO1, Leukocyte adhesion receptor p150,95, Leukocyte surface antigen p150,95, alpha subunit, MAC1A, Macrophage antigen alpha polypeptide, MO1A, Myeloid membrane antigen, alpha subunit, Neutrophil adherence receptor alpha M subunit, p150 95 integrin alpha chain, SLEB6, ITAM_HUMAN, c equivalent, Integrin αM.
Background: This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
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基因ID
- 3684
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UniProt
- P11215
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途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
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