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CAMKII gamma 抗体

CAMK2G 适用: 人, 大鼠, 小鼠 WB, IHC, IHC (p), IF (cc) 宿主: 兔 Monoclonal 1H12 unconjugated
产品编号 ABIN6942340
发货至: 中国
  • 抗原 See all CAMKII gamma (CAMK2G) 抗体
    CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 52
    • 29
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    克隆类型
    • 48
    • 34
    单克隆
    标记
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    This CAMKII gamma antibody is un-conjugated
    应用范围
    • 53
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Human CaMKII between 200-300 amino acids
    克隆位点
    1H12
    亚型
    IgG
    Top Product
    Discover our top product CAMK2G Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))
    别名
    CaMKII (CAMK2G 产品)
    别名
    CAMK antibody, CAMK-II antibody, CAMKG antibody, 5930429P18Rik antibody, Camkg antibody, calcium/calmodulin dependent protein kinase II gamma antibody, calcium/calmodulin-dependent protein kinase II gamma antibody, CAMK2G antibody, Camk2g antibody
    背景

    Synonyms: Calcium/calmodulin-dependent protein kinase type II subunit alpha, Calcium/calmodulin-dependent protein kinase type II subunit beta, Calcium/calmodulin-dependent protein kinase type II subunit gamma, Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968, CaM kinase II subunit beta, CaMK-II subunit beta, CAMK2B, CAM2, CAMK2, CAMKB, CaM kinase II subunit gamma, CaMK-II subunit gamma, CAMK2G, CAMK, CAMK-II, CAMKG, CaM kinase II subunit delta, CaMK-II subunit delta, CAMK2D, CAMKD

    Background: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2.

    基因ID
    816
    UniProt
    Q13554
    途径
    WNT signaling, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity
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