CAMKII gamma 抗体
Quick Overview for CAMKII gamma 抗体 (ABIN6942340)
抗原
See all CAMKII gamma (CAMK2G) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            交叉反应
- 人, 小鼠, 大鼠
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                                            纯化方法
- Purified by Protein A.
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                                            免疫原
- Human CaMKII between 200-300 amino acids
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                                            亚型
- IgG
 
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                                            应用备注
- 
                        WB 1:300-5000
 IHC-P 1:200-400
 IF(ICC) 1:50-200
 IHC()
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
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                                            缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C for 12 months.
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                                            有效期
- 12 months
 
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    - CAMKII gamma (CAMK2G) (Calcium/calmodulin-Dependent Protein Kinase II gamma (CAMK2G))
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                                            别名
- CaMKII
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                                            背景
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                        Synonyms: Calcium/calmodulin-dependent protein kinase type II subunit alpha, Calcium/calmodulin-dependent protein kinase type II subunit beta, Calcium/calmodulin-dependent protein kinase type II subunit gamma, Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968, CaM kinase II subunit beta, CaMK-II subunit beta, CAMK2B, CAM2, CAMK2, CAMKB, CaM kinase II subunit gamma, CaMK-II subunit gamma, CAMK2G, CAMK, CAMK-II, CAMKG, CaM kinase II subunit delta, CaMK-II subunit delta, CAMK2D, CAMKD Background: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. This structural function is required for correct targeting of CaMK2A, which acts downstream of NMDAR to promote dendritic spine and synapse formation and maintain synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. In developing hippocampal neurons, promotes arborization of the dendritic tree and in mature neurons, promotes dendritic remodeling. Participates in the modulation of skeletal muscle function in response to exercise. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of triadin, a ryanodine receptor-coupling factor, and phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2. 
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                                            基因ID
- 816
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                                            UniProt
- Q13554
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                                            途径
- WNT signaling, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity
 抗原
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