FGF2 抗体 (AA 143-288) (Cy3)
Quick Overview for FGF2 抗体 (AA 143-288) (Cy3) (ABIN6942279)
抗原
See all FGF2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 143-288
-
交叉反应
- 犬, 人, 小鼠, 大鼠
-
预测反应
- Cow,Sheep,Pig,Guinea Pig
-
纯化方法
- Purified by Protein A.
-
免疫原
- Full length of human bFGF Recombinded.
-
亚型
- IgG
-
-
-
-
应用备注
-
FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
-
别名
- bFGF
-
背景
-
Synonyms: Basic fibroblast growth factor, FGF basic, FGF-basic, BFGF, FGF-2, FGF B, FGF2, FGF2 basic, FGFB, Fibroblast growth factor 2 (basic), HBGF 2, HBGF-2, HBGF2, HBGH 2, HBGH2, Heparin binding growth factor 2 precursor, Prostatropin, FGF2_HUMAN.
Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008].
-
基因ID
- 2247
-
UniProt
- P09038
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
抗原
-