BAZ1B 抗体
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- 抗原 See all BAZ1B 抗体
- BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This BAZ1B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within C-terminal human BAZ1B.
- 克隆位点
- 5G1
- 亚型
- IgG
- Top Product
- Discover our top product BAZ1B Primary Antibody
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- 应用备注
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WB 1:300-5000
FCM 1:20-100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
- 别名
- BAZ1B (BAZ1B 产品)
- 别名
- BAZ1B antibody, wstf antibody, wbscr9 antibody, wbscr10 antibody, LOC100220420 antibody, WBSCR10 antibody, WBSCR9 antibody, WSTF antibody, C87820 antibody, Wbscr9 antibody, fi60d02 antibody, im:7137554 antibody, wu:fi60d02 antibody, bromodomain adjacent to zinc finger domain 1B antibody, bromodomain adjacent to zinc finger domain, 1B antibody, bromodomain adjacent to zinc finger domain 1B S homeolog antibody, BAZ1B antibody, baz1b antibody, Baz1b antibody, baz1b.S antibody
- 背景
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Synonyms: Tyrosine-protein kinase BAZ1B, Bromodomain adjacent to zinc finger domain protein 1B, Williams syndrome transcription factor, Williams-Beuren syndrome chromosomal region 10 protein, Williams-Beuren syndrome chromosomal region 9 protein, hWALp2, BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF
Background: Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication.
- 基因ID
- 9031
- UniProt
- Q9UIG0
- 途径
- Nuclear Hormone Receptor Binding, Chromatin Binding
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