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BAZ1B 抗体

BAZ1B 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Monoclonal 5G1 unconjugated
产品编号 ABIN6942236
发货至: 中国
  • 抗原 See all BAZ1B 抗体
    BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
    适用
    • 53
    • 13
    • 12
    • 3
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 49
    • 4
    克隆类型
    • 42
    • 11
    单克隆
    标记
    • 22
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    • 2
    • 2
    • 2
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    This BAZ1B antibody is un-conjugated
    应用范围
    • 26
    • 22
    • 14
    • 13
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
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    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within C-terminal human BAZ1B.
    克隆位点
    5G1
    亚型
    IgG
    Top Product
    Discover our top product BAZ1B Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
    别名
    BAZ1B (BAZ1B 产品)
    别名
    BAZ1B antibody, wstf antibody, wbscr9 antibody, wbscr10 antibody, LOC100220420 antibody, WBSCR10 antibody, WBSCR9 antibody, WSTF antibody, C87820 antibody, Wbscr9 antibody, fi60d02 antibody, im:7137554 antibody, wu:fi60d02 antibody, bromodomain adjacent to zinc finger domain 1B antibody, bromodomain adjacent to zinc finger domain, 1B antibody, bromodomain adjacent to zinc finger domain 1B S homeolog antibody, BAZ1B antibody, baz1b antibody, Baz1b antibody, baz1b.S antibody
    背景

    Synonyms: Tyrosine-protein kinase BAZ1B, Bromodomain adjacent to zinc finger domain protein 1B, Williams syndrome transcription factor, Williams-Beuren syndrome chromosomal region 10 protein, Williams-Beuren syndrome chromosomal region 9 protein, hWALp2, BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF

    Background: Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication.

    基因ID
    9031
    UniProt
    Q9UIG0
    途径
    Nuclear Hormone Receptor Binding, Chromatin Binding
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