CD4 抗体
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北京 101111
Quick Overview for CD4 抗体 (ABIN6941473)
抗原
See all CD4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD4, Mouse (T-Cell Marker) Antibody
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特异性
- CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.
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无交叉反应
- 人
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Mouse CTL clone V4
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亚型
- IgG2b, kappa
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anti-CD4 (CD4) (AA 385-457) antibody
CD4 适用: 人 FACS, WB, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD4 (CD4) antibodyCD4 适用: 人, 小鼠, 大鼠, 猴, 小鸡, 犬, 兔, Cow, 绵羊, 豚鼠, 山羊, Pig, 马, Avian, 驴, Hamster WB, IHC (fro), IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-CD4 (CD4) (AA 231-330) antibodyCD4 适用: 小鼠 FACS, WB, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD4 (CD4) (N-Term) antibodyCD4 适用: 人 FACS, WB, MS 宿主: 小鼠 Monoclonal MEM-241 unconjugated
anti-CD4 (CD4) antibodyCD4 适用: 人, 小鼠, 大鼠 IHC 宿主: 小鼠 Monoclonal unconjugated
anti-CD4 (CD4) (AA 301-400) antibodyCD4 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD4 (CD4) (AA 26-200) antibodyCD4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CD4 (CD4) antibody (PE)CD4 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal OX-35 PE
anti-CD4 (CD4) antibodyCD4 适用: 小鼠 FACS, IP, ICC, IHC (fro), Func 宿主: 大鼠 Monoclonal GK1-5 unconjugated
anti-CD4 (CD4) (N-Term) antibody (FITC)CD4 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-241 FITC
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应用备注
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Positive Control: Spleen, Thymus or Lymph Node.
Known Application: ELISA (For coating, order Ab without BSA & Azide), Neutralization Studies (Order Ab without BSA & Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CD4
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别名
- CD4 (T-Cell Marker)
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背景
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CD4 (L3T4), CD4, CD4+ Lymphocyte deficiency, included, Leu3, Ly-4, Lymphocyte antigen CD4, p55, T cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
Spleen, Thymus or Lymph Node.
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分子量
- 55kDa
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基因ID
- 12504, 2209
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UniProt
- P06332
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途径
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
抗原
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