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CD37 抗体

This anti-CD37 antibody is a 小鼠 单克隆 antibody detecting CD37 in FACS, IF 和 Func. Suitable for 人.
产品编号 ABIN6941181
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD37 抗体 (ABIN6941181)

抗原

See all CD37 (TSPAN26) 抗体
CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD37 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

克隆位点

IPO-24
  • 特异性

    Recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).

    纯化方法

    Purified by Protein A/G

    免疫原

    Spleen cells of a patient with hairy cell leukemia

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Daudi, Raji, Namalva, Ramos cells and human lymphocytes. Human tonsil and lymph node.

    Known Application: Functional Studies (Order Ab without Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

    别名

    CD37

    分子量

    33-55kDa

    基因ID

    951

    UniProt

    P11049

    途径

    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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