CD4 抗体
Quick Overview for CD4 抗体 (ABIN6941040)
抗原
See all CD4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Recognizes a protein of 55 kDa, identified as CD4. It is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
-
纯化方法
- Purified by Protein A/G
-
免疫原
- Human peripheral lymphocytes
-
亚型
- IgG2a kappa
-
-
-
-
应用备注
-
Positive Control: Human peripheral blood mononuclear cells (PBMCs), CCRF-CEM or HL-60. Lymph node or tonsil.
Known Application: Functional Studies (Order Ab without azide), Flow Cytometry (1-2 μg/million cells in 0.1ml), Immunofluorescence (1-2 μg/mL) Optimal dilution for a specific application should be determined.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- CD4
-
别名
- CD4
-
分子量
- 55kDa
-
基因ID
- 920
-
UniProt
- P01730
-
途径
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
抗原
-