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CD1c 抗体

This 小鼠 单克隆 anti-CD1c antibody (Clone CD1C-1603) specifically detects CD1c in ELISA 和 Coat. The antibody is reactive with 人 samples.
产品编号 ABIN6941008
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD1c 抗体 (ABIN6941008)

抗原

See all CD1c (CD1C) 抗体
CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD1c antibody is un-conjugated

应用范围

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ELISA, Coating (Coat)

克隆位点

CD1C-1603
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant full-length human CD1c protein

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Expressed on cortical thymocytes, on certain T-cell leukemias and in various other tissues.

    Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))

    别名

    CD1C

    背景

    The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with -2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Specifically, CD1A is a marker for Langerhans cell histiocytosis (LCH) and is found on interdigitating cells. Adaptor-protein complexes and CD1-associated chaperones control CD1 trafficking, and the development and activation of CD1-restricted T cells. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells. The human CD1 genes are all closely linked in a cluster mapping at chromosome 1q23.1

    分子量

    43kDa

    基因ID

    911

    UniProt

    P29017
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