CAPNL1 抗体
Quick Overview for CAPNL1 抗体 (ABIN6940954)
抗原
See all CAPNL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant full-length human CAPN1 protein
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亚型
- IgG1 kappa
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anti-Calpain 1, Large Subunit (CAPNL1) antibody
CAPNL1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 20-330) antibodyCAPNL1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 501-714) antibodyCAPNL1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5B2G10 unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 387-694) antibodyCAPNL1 适用: 大鼠 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 387-694) antibodyCAPNL1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 501-714) antibodyCAPNL1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1E6G9 unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 312-326), (Middle Region) antibodyCAPNL1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 387-694) antibodyCAPNL1 适用: 小鼠 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 75-343) antibodyCAPNL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 1, Large Subunit (CAPNL1) (AA 20-330), (Catalytic Subunit) antibodyCAPNL1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: HeLa cells. Skin or Tonsil.
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CAPNL1 (Calpain 1, Large Subunit (CAPNL1))
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别名
- CAPN1
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背景
- Calpain 1 is an intracellular calcium-dependent protease that cleaves cytoskeletal and sub-membranous proteins. Calpains are non-lysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2+- dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit and one of three large catalytic subunits, designated Calpain 1, Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpain 1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction.
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分子量
- 80kDa
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基因ID
- 823
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UniProt
- P07384
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途径
- Apoptosis
抗原
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