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Recombinant TIMP2 抗体 (N-Term)

This anti-TIMP2 antibody is a 兔 单克隆 antibody detecting TIMP2 in IHC 和 StM. Suitable for 人, 大鼠, 小鼠, Cow, 斑马鱼, 兔 和 豚鼠.
产品编号 ABIN6940739
发货至: 中国

Quick Overview for Recombinant TIMP2 抗体 (N-Term) (ABIN6940739)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

抗体类型

Recombinant Antibody

适用

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人, 大鼠, 小鼠, Cow, 斑马鱼, 兔, 豚鼠

宿主

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克隆类型

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单克隆

标记

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This TIMP2 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

TIMP2-2488R
  • 抗原表位

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    AA 56-66, N-Term

    特异性

    It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

    纯化方法

    Purified by Protein A/G

    免疫原

    A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)

    亚型

    IgG
  • 应用备注

    Positive Control: HeLa cells. Normal Placenta. Breast, Colon, Endometrial, Prostate or Ovarian Carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP2

    分子量

    21kDa

    基因ID

    7077

    UniProt

    P16035

    途径

    cAMP Metabolic Process
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