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Recombinant TFF1 抗体

TFF1 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal rTFF1-1091 unconjugated Recombinant Antibody
产品编号 ABIN6940691
发货至: 中国
  • 抗原 See all TFF1 抗体
    TFF1 (Trefoil Factor 1 (TFF1))
    抗体类型
    Recombinant Antibody
    适用
    • 83
    • 18
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    • 13
    • 9
    宿主
    • 46
    • 44
    • 1
    小鼠
    克隆类型
    • 49
    • 42
    单克隆
    标记
    • 58
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    This TFF1 antibody is un-conjugated
    应用范围
    • 45
    • 36
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    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    特异性
    It recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60 % of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant full-length human TFF1 protein
    克隆位点
    RTFF1-1091
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TFF1 Primary Antibody
  • 应用备注

    Positive Control: MCF-7 cells (FACS/IF). Human breast or ovarian carcinoma (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed. Not suitable for frozen tissues.) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    TFF1 (Trefoil Factor 1 (TFF1))
    别名
    TFF1 (TFF1 产品)
    别名
    BCEI antibody, D21S21 antibody, HP1.A antibody, HPS2 antibody, pNR-2 antibody, pS2 antibody, Bcei antibody, PS2 antibody, bcei antibody, d21s21 antibody, hp1.a antibody, hps2 antibody, p1 antibody, p1-a antibody, pnr-2 antibody, ps2 antibody, tff1 antibody, xP1 antibody, xp1-L antibody, xp1 antibody, TFF1 antibody, Ps2 antibody, trefoil factor 1 antibody, trefoil factor 1 S homeolog antibody, trefoil factor 1, gene 2 S homeolog antibody, TFF1 antibody, Tff1 antibody, tff1.S antibody, tff1.2.S antibody, LOC100358238 antibody
    分子量
    6.5kDa
    基因ID
    7031
    UniProt
    P04155
    途径
    EGFR Signaling Pathway
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