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Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体

This anti- antibody is a 小鼠 单克隆 antibody detecting in WB, FACS, IHC, IF 和 StM. Suitable for 人.
产品编号 ABIN6940652
发货至: 中国

Quick Overview for Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体 (ABIN6940652)

抗原

See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体
Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

适用

  • 126
  • 36
  • 34
  • 1

宿主

  • 67
  • 59
小鼠

克隆类型

  • 115
  • 11
单克隆

标记

  • 46
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
非结合性

应用范围

  • 123
  • 86
  • 79
  • 75
  • 43
  • 20
  • 14
  • 6
  • 5
  • 5
  • 3
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)

克隆位点

SPTBN2-1583
  • 抗原表位

    • 113
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-475

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment (around aa356-475) of human SPTBN2 protein (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: PANC-1, HeLa cells. Pancreas or Liver.

    Known Application: Flow Cytometry (1-2 μg/million cells), (,Immunofluorescence (0.5-1 μg/mL), ,Western Blot (0.5-1.0 μg/mL),Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

    别名

    SPTBN2

    背景

    Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin and spectrin are present in erythrocytes, whereas spectrin II (also designated fodrin ) and spectrin I (also designated fodrin ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin III is highly homologous to both spectrin I and spectrin II. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.

    分子量

    246kDa

    基因ID

    6712

    UniProt

    O15020

    途径

    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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