RNLS 抗体 (AA 34-235)
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- 抗原 See all RNLS 抗体
- RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
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抗原表位
- AA 34-235
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This RNLS antibody is un-conjugated
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应用范围
- ELISA, Coating (Coat)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human RNLS protein fragment (around aa 34-235) (exact sequence is proprietary)
- 克隆位点
- RNLS-1940
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product RNLS Primary Antibody
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- 应用备注
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Positive Control: 293T cells. Heart or Kidney.
Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
- 别名
- RNLS (RNLS 产品)
- 别名
- zgc:92286 antibody, C10orf59 antibody, RENALASE antibody, 6530404N21Rik antibody, AI452315 antibody, AW060440 antibody, RGD1309804 antibody, renalase, FAD dependent amine oxidase antibody, renalase, FAD-dependent amine oxidase antibody, RNLS antibody, rnls antibody, Rnls antibody
- 背景
- Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events.
- 分子量
- 38kDa
- 基因ID
- 55328
- UniProt
- Q5VYX0
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