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- 抗原 See all ACP5 抗体
- ACP5 (Acid Phosphatase 5, Tartrate Resistant (ACP5))
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ACP5 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
- 特异性
- It recognizes a protein of 35 kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This MAb reacts with both the isoforms. Serum TRAcP 5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis.Serum TRAcP 5b is produced from osteoclasts and elevated during bone resorption. TRAcP is an iron containing glycoprotein, which catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is the most basic of the acid phosphatases and is the only form not inhibited by L(+)-tartrate. TRAcP is synthesized as a latent proenzyme and is activated by proteolytic cleavage and reduction. Normally, TRAcP is highly expressed by osteoclasts, activated macrophages, neurons and endometrium during pregnancy. Expression of TRAcP is increased in certain pathological conditions such as Leukemic Reticuloendotheliosis (Hairy Cell Leukemia), Gaucher's Disease, HIV-induced Encephalopathy, Osteoclastoma and in osteoporosis and metabolic bone diseases. Anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant full-length human ACP5 protein
- 克隆位点
- SPM601
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product ACP5 Primary Antibody
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anti-Acid Phosphatase 5, Tartrate Resistant (ACP5) (AA 221-325) antibody
ACP5 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5C5E7 unconjugated
anti-Acid Phosphatase 5, Tartrate Resistant (ACP5) (AA 221-325) antibodyACP5 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7E6A11 unconjugated
anti-Acid Phosphatase 5, Tartrate Resistant (ACP5) (AA 76-325) antibodyACP5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Acid Phosphatase 5, Tartrate Resistant (ACP5) (AA 221-325) antibodyACP5 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS 宿主: 小鼠 Monoclonal unconjugated
anti-Acid Phosphatase 5, Tartrate Resistant (ACP5) (AA 29-296) antibodyACP5 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acid Phosphatase 5, Tartrate Resistant (ACP5) (AA 1-325) antibodyACP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Acid Phosphatase 5, Tartrate Resistant (ACP5) antibodyACP5 适用: 人, 小鼠, 大鼠 IHC, StM 宿主: 小鼠 Monoclonal rACP5-1070 unconjugated Recombinant Antibody
anti-Acid Phosphatase 5, Tartrate Resistant (ACP5) (AA 72-158) antibodyACP5 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D9 unconjugated
anti-Acid Phosphatase 5, Tartrate Resistant (ACP5) (N-Term) antibodyACP5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Acid Phosphatase 5, Tartrate Resistant (ACP5) (AA 74-321) antibodyACP5 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal unconjugated
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- 应用备注
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Positive Control: HepG2, 293T, K562 or RPMI-8226 cells. Spleen from Hairy Cell Leukemia (HCL) patient.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- ACP5 (Acid Phosphatase 5, Tartrate Resistant (ACP5))
- 别名
- ACP5 (ACP5 产品)
- 别名
- SPENCDI antibody, TRAP antibody, acp5 antibody, sb:cb576 antibody, zgc:63825 antibody, wu:fb19f01 antibody, wu:fb30b03 antibody, wu:fi14e01 antibody, wu:fj66f03 antibody, MGC78938 antibody, MGC89674 antibody, TR-AP antibody, zgc:92339 antibody, TRACP antibody, TTRRAP antibody, Trap antibody, UF antibody, acid phosphatase 5, tartrate resistant antibody, acid phosphatase 5a, tartrate resistant antibody, acid phosphatase 5, tartrate resistant S homeolog antibody, tartrate resistant acid phosphatase antibody, Tartrate-resistant acid phosphatase type 5 antibody, tartrate-resistant acid phosphatase type 5 antibody, acid phosphatase 5b, tartrate resistant antibody, ACP5 antibody, acp5a antibody, acp5.S antibody, acp5 antibody, NAEGRDRAFT_81291 antibody, ppa5 antibody, LOC100282899 antibody, acp5b antibody, Acp5 antibody
- 分子量
- 35kDa
- 基因ID
- 54
- UniProt
- P13686
- 途径
- Transition Metal Ion Homeostasis
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