PD-1 抗体
Quick Overview for PD-1 抗体 (ABIN6940268)
抗原
See all PD-1 (PDCD1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
 - Purified by Protein A/G
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免疫原
 - Recombinant full-length human PDCD1 protein
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亚型
 - IgG1 kappa
 
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应用备注
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Positive Control: TY cells. Tonsil.
Known Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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限制
 - 仅限研究用
 
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浓度
 - 200 μg/mL
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缓冲液
 - 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-80 °C
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储存方法
 - Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
 - 24 months
 
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- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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别名
 - PDCD1
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背景
 - PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
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分子量
 - 55kDa
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基因ID
 - 5133
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UniProt
 - Q15116
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途径
 - Cancer Immune Checkpoints
 
抗原
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