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PAX6 抗体 (N-Term)

PAX6 适用: 人, 小鼠, 大鼠, 小鸡 WB, IF, FACS 宿主: 小鼠 Monoclonal PAX6-498 unconjugated
产品编号 ABIN6940257
发货至: 中国
  • 抗原 See all PAX6 抗体
    PAX6 (Paired Box 6 (PAX6))
    抗原表位
    • 26
    • 22
    • 16
    • 15
    • 10
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-300, N-Term
    适用
    • 114
    • 71
    • 67
    • 14
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 小鸡
    宿主
    • 96
    • 38
    • 1
    小鼠
    克隆类型
    • 86
    • 48
    单克隆
    标记
    • 70
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PAX6 antibody is un-conjugated
    应用范围
    • 97
    • 49
    • 46
    • 40
    • 30
    • 26
    • 15
    • 14
    • 13
    • 9
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    特异性
    Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment (N-terminus, aa 1-300) of human PAX6 protein
    克隆位点
    PAX6-498
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PAX6 Primary Antibody
  • 应用备注

    Positive Control: Pancreas or Cerebellum.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    PAX6 (Paired Box 6 (PAX6))
    别名
    PAX6 (PAX6 产品)
    别名
    pax6 antibody, an2 antibody, mgda antibody, wagr antibody, pax-6 antibody, pax6a antibody, xpax6 antibody, XLPAX6 antibody, MGC52531 antibody, PAX-6 antibody, AN antibody, AN2 antibody, D11S812E antibody, MGDA antibody, WAGR antibody, Pax-6 antibody, pax6b antibody, 1500038E17Rik antibody, AEY11 antibody, Dey antibody, Gsfaey11 antibody, Sey antibody, PAXZF-A antibody, Pax6.1 antibody, cb280 antibody, fc20e07 antibody, pax-a antibody, pax[zf-a] antibody, paxzfa antibody, wu:fc20e07 antibody, zfpax-6a antibody, zfpax-6b antibody, paired box 6 antibody, paired box 6 L homeolog antibody, paired box 6 S homeolog antibody, paired box 6a antibody, PAX6 antibody, pax6 antibody, Pax6 antibody, pax6.L antibody, pax6.S antibody, pax6a antibody
    分子量
    47kDa
    基因ID
    5080
    UniProt
    P26367
    途径
    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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