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- 抗原 See all NUMA1 抗体
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NUMA1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
- 特异性
- Recognizes a phosphorylated protein of 228 kDa, identified as nuclear mitotic apparatus protein (NuMA). Its epitope is resistant to phosphatases. NuMA is intra-nuclear protein and present in nucleus during interphase. At the onset of mitosis, it redistributes from the nucleus to two centrosomal structures that later will become part of the mitotic spindle pole. After anaphase, the protein redistributes from the spindle polar region into reforming nucleus. NuMA is an essential protein during mitosis for the terminal phases of chromosome separation and/or nuclear reassembly. Recently a study shows that NuMA is cleaved to a 180 to 200 kDa during apoptosis. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 has been detected in patients with acute promyelocytic leukemia.
- 免疫原
- Colon carcinoma 174T cells
- 克隆位点
- A73-B-D12
- 亚型
- IgM kappa
- Top Product
- Discover our top product NUMA1 Primary Antibody
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anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-309) antibody
NUMA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (N-Term) antibodyNUMA1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 627-870) antibodyNUMA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-1193) antibodyNUMA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 200-306) antibodyNUMA1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-1193) antibodyNUMA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibodyNUMA1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (N-Term) antibodyNUMA1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1700-2115) antibodyNUMA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1700-2115) antibodyNUMA1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
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- 应用备注
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Positive Control: Exponentially growing any cultured human cells. Tonsil or lymph node.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM citrate buffer, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 200 μg/mL of Ab Purified from Bioreactor Concentrate by PEG precipitation. Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
- 别名
- NUMA1 (NUMA1 产品)
- 别名
- NUMA antibody, 6720401E04Rik antibody, AA764025 antibody, AL022610 antibody, AU014979 antibody, NUMA1 antibody, NuMA antibody, SP-H antibody, numa antibody, numa1 antibody, nuclear mitotic apparatus protein 1 antibody, nuclear mitotic apparatus protein 1 S homeolog antibody, NUMA1 antibody, Numa1 antibody, numa1 antibody, numa1.S antibody
- 分子量
- 228kDa
- 基因ID
- 4926
- UniProt
- Q14980
- 途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
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