c-MYC 抗体 (C-Term)
Quick Overview for c-MYC 抗体 (C-Term) (ABIN6940148)
抗原
See all c-MYC (MYC) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 408-439, C-Term
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特异性
- It recognizes a transcription factor of 64-67 kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.
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无交叉反应
- 小鸡, 小鼠, 大鼠
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纯化方法
- Purified by Protein A/G
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免疫原
- A synthetic peptide, corresponding to aa 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from C-terminus of human c-myc, coupled to KLH.
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亚型
- IgG1 kappa
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anti-Myc Proto-Oncogene protein (MYC) (AA 330-439) antibody
MYC 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Myc Proto-Oncogene protein (MYC) (Center) antibodyMYC 适用: 人, 小鼠 WB, IF, IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 31-80) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pThr58) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (pSer62) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) antibodyKO Validated MYC 适用: 人 WB, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (AA 101-200) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) (N-Term) antibodyMYC 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myc Proto-Oncogene protein (MYC) antibodyMYC 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated
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应用备注
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Positive Control: HL-60 cells. Breast carcinoma.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
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别名
- Myc Proto-Oncogene protein
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分子量
- 62-64kDa
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基因ID
- 4609
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UniProt
- P01106
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途径
- p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
抗原
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