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MUC5AC 抗体

This anti-MUC5AC antibody is a 小鼠 单克隆 antibody detecting MUC5AC in IHC 和 StM. Suitable for 人, 小鼠, 大鼠, 猴, Cat, 兔, 小鸡, Pig 和 Hedgehog.
产品编号 ABIN6940128
发货至: 中国

Quick Overview for MUC5AC 抗体 (ABIN6940128)

抗原

See all MUC5AC 抗体
MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

适用

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人, 小鼠, 大鼠, 猴, Cat, 兔, 小鸡, Pig, Hedgehog

宿主

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小鼠

克隆类型

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单克隆

标记

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This MUC5AC antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

45M1
  • 特异性

    This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

    无交叉反应

    纯化方法

    Purified by Protein A/G

    免疫原

    M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: Human colon or stomach (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

    别名

    MUC5AC

    分子量

    >1,000kDa

    基因ID

    4586

    UniProt

    P98088
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