MMP2 抗体 (AA 444-575)
Quick Overview for MMP2 抗体 (AA 444-575) (ABIN6940067)
抗原
See all MMP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 444-575
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特异性
- It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant human MMP2 protein fragment (aa 444-575) (exact sequence is proprietary)
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亚型
- IgG1 kappa
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应用备注
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Positive Control: U-138 MG or U-87 MG cells. Placenta or Colon Carcinoma.
Known Application: Western Blot (0.5-1 μg/mL) Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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别名
- MMP2
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分子量
- 72kDa (Pro), 63kDa (cleaved)
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基因ID
- 4313
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UniProt
- P08253
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途径
- Activation of Innate immune Response
抗原
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