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MMP2 抗体 (AA 444-575)

This anti-MMP2 antibody is a 小鼠 单克隆 antibody detecting MMP2 in WB. Suitable for 人.
产品编号 ABIN6940067
发货至: 中国

Quick Overview for MMP2 抗体 (AA 444-575) (ABIN6940067)

抗原

See all MMP2 抗体
MMP2 (Matrix Metalloproteinase 2 (MMP2))

适用

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宿主

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小鼠

克隆类型

  • 137
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单克隆

标记

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This MMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

MMP2-1501
  • 抗原表位

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    AA 444-575

    特异性

    It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human MMP2 protein fragment (aa 444-575) (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: U-138 MG or U-87 MG cells. Placenta or Colon Carcinoma.

    Known Application: Western Blot (0.5-1 μg/mL) Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    MMP2 (Matrix Metalloproteinase 2 (MMP2))

    别名

    MMP2

    分子量

    72kDa (Pro), 63kDa (cleaved)

    基因ID

    4313

    UniProt

    P08253

    途径

    Activation of Innate immune Response
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