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MME 抗体 (AA 297-483)

This anti-MME antibody is a 小鼠 单克隆 antibody detecting MME in WB, IHC, ELISA, StM 和 Coat. Suitable for 人.
产品编号 ABIN6940060
发货至: 中国

Quick Overview for MME 抗体 (AA 297-483) (ABIN6940060)

抗原

See all MME 抗体
MME (Membrane Metallo-Endopeptidase (MME))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MME antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Staining Methods (StM), Coating (Coat)

克隆位点

MME-1892
  • 抗原表位

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    AA 297-483

    特异性

    Recognizes a 100 kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human CD10 protein fragment (aa297-483) (exact sequence is proprietary)

    亚型

    IgG2c kappa
  • 应用备注

    Positive Control: Tonsil, small intestine or kidney (IHC).

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    MME (Membrane Metallo-Endopeptidase (MME))

    别名

    MME

    物质类

    Chemical

    分子量

    100kDa

    基因ID

    4311

    UniProt

    P08473

    途径

    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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