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MCM6 抗体 (AA 228-368)

This anti-MCM6 antibody is a 小鼠 单克隆 antibody detecting MCM6 in IHC 和 StM. Suitable for 人.
产品编号 ABIN6940016
发货至: 中国

Quick Overview for MCM6 抗体 (AA 228-368) (ABIN6940016)

抗原

See all MCM6 抗体
MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

适用

  • 51
  • 21
  • 15
  • 10
  • 7
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  • 7
  • 4
  • 2
  • 1
  • 1

宿主

  • 40
  • 7
  • 4
小鼠

克隆类型

  • 44
  • 7
单克隆

标记

  • 46
  • 1
  • 1
  • 1
  • 1
  • 1
This MCM6 antibody is un-conjugated

应用范围

  • 46
  • 36
  • 19
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  • 13
  • 10
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  • 3
  • 3
  • 2
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  • 1
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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

MCM6-2999
  • 抗原表位

    • 13
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 228-368

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment (around aa 228-368) of human MCM6 protein (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Human skin or squamous cell carcinoma (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))

    别名

    MCM6

    背景

    The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM6 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. Expression of MCM proteins increases during cell growth, peaking at G1/S phase. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the post-replicative state of the cell. MCM2/MCM6 complexes function as substrates for Cdc2/cyclin B in vitro.

    分子量

    105kDa

    基因ID

    4175

    UniProt

    Q14566

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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