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MCAM 抗体 (AA 226-374)

This anti-MCAM antibody is a 小鼠 单克隆 antibody detecting MCAM in IHC 和 StM. Suitable for 人.
产品编号 ABIN6940014
发货至: 中国

Quick Overview for MCAM 抗体 (AA 226-374) (ABIN6940014)

抗原

See all MCAM 抗体
MCAM (Melanoma Cell Adhesion Molecule (MCAM))

适用

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宿主

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小鼠

克隆类型

  • 115
  • 99
单克隆

标记

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This MCAM antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

MCAM-3048
  • 抗原表位

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    AA 226-374

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human MCAM protein fragment (around aa226-374) (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Human skin or melanoma tissue (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    MCAM (Melanoma Cell Adhesion Molecule (MCAM))

    别名

    MCAM

    背景

    The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80 % of advanced primary human melanomas and correlates well with development of metastatic disease.

    分子量

    130kDa

    基因ID

    4162

    UniProt

    P43121
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