ICAM1 抗体
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北京 101111
Quick Overview for ICAM1 抗体 (ABIN6939680)
抗原
See all ICAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD54 / ICAM-1 Antibody
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特异性
- Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Human monocytes.
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亚型
- IgG1, kappa
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anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 201-300) antibody
ICAM1 适用: 人, 小鼠, 大鼠, 兔 WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 198-537) antibodyICAM1 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) antibodyICAM1 适用: 人, 大鼠, Cow WB, FACS, ELISA, ICC, IHC (p) 宿主: 小鼠 Monoclonal MEM-111 unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 41-464) antibodyICAM1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 18# unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 102-306) antibodyICAM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (pTyr512) antibodyICAM1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 28-268) antibodyICAM1 适用: 人, 小鼠, 大鼠 WB, FACS, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 41-464) antibodyICAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 27-209) antibodyICAM1 适用: Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 313-327) antibodyVerified ICAM1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
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应用备注
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Positive Control: Raji cells, MOLT 4, HeLa or SW480 cells. Human tonsil.
Known Application: Functional Studies (Order Ab without BSA & Azide),Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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别名
- ICAM1
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背景
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CD54, Cell surface glycoprotein P3.58, Human rhinovirus receptor, ICAM-1, Intercellular adhesion molecule 1, Ly 47, Major group rhinovirus receptor, MALA2, MyD10, Surface antigen of activated B cells
HeLa or SW480 cells. Human tonsil., MOLT 4, Raji cells
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分子量
- 85-115kDa
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基因ID
- 3383, 643447
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UniProt
- P05362
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途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
抗原
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