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Annexin a1 抗体

This anti-Annexin a1 antibody (ABIN6939603) is a Mouse Monoclonal antibody detecting Annexin a1 in IHC, FACS, StM. Suitable for Human.
产品编号 ABIN6939603
发货至: 中国

Quick Overview for Annexin a1 抗体 (ABIN6939603)

抗原

See all Annexin a1 (ANXA1) 抗体
Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Annexin a1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)

克隆位点

ANXA1-1671
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant full length human Annexin A1 protein

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: A431 and K562 cell lysates, human esophagus, placenta and prostate tissues.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

    别名

    ANXA1

    背景

    The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

    分子量

    35kDa

    基因ID

    301

    UniProt

    P04083

    途径

    Hormone Transport
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