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Annexin a1 抗体 (AA 2-346)

Name: Annexin a1 抗体 (AA 2-346)
SKU: ABIN3043783
Availability: OutOfStock

ANXA1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Annexin A1 (ANXA1) (AA 2-346) antibody (ABIN3043783) (Annexin a1 抗体 (AA 2-346))

Anti-Annexin A1 Picoband antibody, IHC(P): Human Tonsil Tissue (Annexin a1 抗体 (AA 2-346))

IHC

Anti-Annexin A1 Picoband antibody, IHC(P): Rat Lung Tissue (Annexin a1 抗体 (AA 2-346))

IHC

Anti-Annexin A1 Picoband antibody, All lanes: Anti AnnexinA1 at 0. (Annexin a1 抗体 (AA 2-346))

4 images

(3 references)

产品编号 ABIN3043783

发货至: 中国

Datasheet as PDF

抗原 See all Annexin a1 (ANXA1) 抗体

Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
抗原表位
28

15

9

9

9

7

5

4

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 2-346
适用
129

49

42

11

10

10

9

7

5

2

1

1

1
人, 小鼠, 大鼠
宿主
133

34

8

1
兔
Compatible Secondaries
克隆类型
138

37
多克隆
标记
100

28

14

6

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
This Annexin a1 antibody is un-conjugated
应用范围
133

67

64

27

25

24

24

23

13

13

11

8

7

4

4

4

4

3

3

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

原理

Rabbit IgG polyclonal antibody for Annexin A1(ANXA1) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Annexin A1(ANXA1) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
Gene Name: annexin A1
Protein Name: Annexin A1

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Annexin A1 recombinant protein (Position: A2-N346). Human Annexin A1 shares 88% and 89% amino acid (aa) sequences identity with mouse and rat Annexin A1, respectively.

亚型

IgG

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anti-Annexin A1 (ANXA1) (AA 1-346) antibody
ANXA1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Annexin A1 (ANXA1) antibody
ANXA1 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal ANXA1-3566 unconjugated

anti-Annexin A1 (ANXA1) (AA 144-248) antibody
ANXA1 适用: 人, 小鼠, 猴 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2F1 unconjugated

anti-Annexin A1 (ANXA1) antibody
ANXA1 适用: 人 WB, IP, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Annexin A1 (ANXA1) antibody
KO Validated ANXA1 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Annexin A1 (ANXA1) antibody
ANXA1 适用: 人 IHC, FACS, StM 宿主: 小鼠 Monoclonal ANXA1-1671 unconjugated

anti-Annexin A1 (ANXA1) (AA 1-346) antibody
ANXA1 适用: 人 WB, IHC (p), IF 宿主: 小鼠 Polyclonal unconjugated

anti-Annexin A1 (ANXA1) (AA 1-346) antibody
ANXA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D11 unconjugated

anti-Annexin A1 (ANXA1) (C-Term) antibody
Verified ANXA1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Annexin A1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Mouse
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Zhang, Wu, Zha, Zhao, Feng: "The prognostic value and clinicopathological features of sarcomatoid differentiation in patients with renal cell carcinoma: a systematic review and meta-analysis." in: Cancer management and research, Vol. 10, pp. 1687-1703, (2018) (PubMed).

Manville, Abbott: "Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket." in: Nature communications, Vol. 9, Issue 1, pp. 3845, (2018) (PubMed).

Mohamed, Idris, Ahmed, Åstrøm, Mustafa, Ibrahim, Mustafa: "Influence of type 2 diabetes on local production of inflammatory molecules in adults with and without chronic periodontitis: a cross-sectional study." in: BMC oral health, Vol. 15, pp. 86, (2015) (PubMed).
抗原

Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

别名

ANXA1 (ANXA1 产品)

别名

anx1a antibody, anxa1 antibody, wu:fa01d11 antibody, wu:fa05d11 antibody, wu:fk69h01 antibody, MGC64363 antibody, anx1 antibody, lpc1 antibody, MGC89164 antibody, ANXA1 antibody, ANX1 antibody, LPC1 antibody, p35 antibody, Anx-1 antibody, Anx-A1 antibody, C430014K04Rik antibody, Lpc-1 antibody, Lpc1 antibody, Anx1 antibody, annexin A1a antibody, annexin A1 antibody, annexin A1 L homeolog antibody, Annexin A1 antibody, anxa1a antibody, anxa1 antibody, anxa1.L antibody, ANXA1 antibody, LOC100335033 antibody, Anxa1 antibody

背景

ANXA1, also known as lipocortin I or Annexin A1, is a protein that in humans is encoded by the ANXA1 gene. It is mapped to 9q21.13. ANXA1 belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. ANXA1 protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Lower peptide concentrations possibly found in inflammatory situations elicit Ca(2+) transients without fully activating the mitogen-activated protein kinase pathway. This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge. These findings identified ANXA1 peptides as novel, endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects.

Synonyms: Annexin 1 antibody|Annexin A1 antibody|Annexin I (lipocortin I) antibody|Annexin I antibody|Annexin-1 antibody|AnnexinA1 antibody|AnnexinI antibody|ANX 1 antibody|ANX A1 antibody|ANX1 antibody|ANXA 1 antibody|ANXA1 antibody|ANXA1 protein antibody|ANXA1_HUMAN antibody|Calpactin 2 antibody|Calpactin II antibody|Calpactin-2 antibody|CalpactinII antibody|Chromobindin 9 antibody|Chromobindin-9 antibody|Chromobindin9 antibody|Lipocortin 1 antibody|Lipocortin I antibody|Lipocortin1 antibody|LipocortinI antibody|LPC 1 antibody|LPC1 antibody|p35 antibody|Phospholipase A2 inhibitory protein antibody

基因ID

301

UniProt

P04083

途径

Hormone Transport