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Annexin a1 抗体 (AA 2-346)

Name: Annexin a1 抗体 (AA 2-346)
SKU: ABIN3043783
Availability: OutOfStock

This 兔多克隆 antibody specifically detects Annexin a1 in WB 和 IHC. It exhibits reactivity toward 人, 大鼠和猴. It has been mentioned in 3+ publications

Western blot analysis of Annexin A1 using anti-Annexin A1 antibody (ABIN3043783). (Annexin a1 抗体 (AA 2-346))

Anti-Annexin A1 Picoband antibody, IHC(P): Human Tonsil Tissue (Annexin a1 抗体 (AA 2-346))

IHC

Western Blotting (WB) image for anti-Annexin A1 (ANXA1) (AA 2-346) antibody (ABIN3043783) (Annexin a1 抗体 (AA 2-346))

Anti-Annexin A1 Picoband antibody, IHC(P): Rat Lung Tissue (Annexin a1 抗体 (AA 2-346))

IHC

Anti-Annexin A1 Picoband antibody, All lanes: Anti AnnexinA1 at 0. (Annexin a1 抗体 (AA 2-346))

Western blot analysis of Annexin A1/ANXA1 using anti-Annexin A1/ANXA1 antibody (ABIN3043783). (Annexin a1 抗体 (AA 2-346))

6 images

(3 references)

产品编号 ABIN3043783

发货至: 中国

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Quick Overview for Annexin a1 抗体 (AA 2-346) (ABIN3043783)

抗原

See all Annexin a1 (ANXA1) 抗体

Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

适用

人, 大鼠, 猴

宿主

兔

克隆类型

多克隆

标记

This Annexin a1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product ANXA1 Primary Antibody

抗原表位
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AA 2-346

原理

Anti-Annexin A1/ANXA1 Antibody

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

Human Annexin A1 shares 88%,89% amino acid (aa) sequences identity with mouse,rat Annexin A1,respectively.

产品特性

Anti-Annexin A1/ANXA1 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Monkey, Rat.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Annexin A1 recombinant protein (Position: A2-N346). Human Annexin A1 shares 88% and 89% amino acid (aa) sequences identity with mouse and rat Annexin A1, respectively.

亚型

IgG
anti-Annexin A1 (ANXA1) (AA 6-346) antibody
ANXA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Annexin A1 (ANXA1) (AA 1-346) antibody
ANXA1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-Annexin A1 (ANXA1) antibody
ANXA1 适用: 人 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal ANXA1-3566 unconjugated

anti-Annexin A1 (ANXA1) (AA 144-248) antibody
ANXA1 适用: 人, 小鼠, 猴 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2F1 unconjugated

anti-Annexin A1 (ANXA1) antibody
KD Validated ANXA1 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB6815 unconjugated Recombinant Antibody

anti-Annexin A1 (ANXA1) antibody
ANXA1 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Annexin A1 (ANXA1) (C-Term) antibody
Verified ANXA1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Annexin A1 (ANXA1) (AA 1-346) antibody
ANXA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated

anti-Annexin A1 (ANXA1) (AA 1-346) antibody
ANXA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D11 unconjugated

anti-Annexin A1 (ANXA1) antibody
ANXA1 适用: 人 WB, IHC, FACS, IF 宿主: 小鼠 Monoclonal ANXA1-1671 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Monkey, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Zhang, Wu, Zha, Zhao, Feng: "The prognostic value and clinicopathological features of sarcomatoid differentiation in patients with renal cell carcinoma: a systematic review and meta-analysis." in: Cancer management and research, Vol. 10, pp. 1687-1703, (2018) (PubMed).

Manville, Abbott: "Ancient and modern anticonvulsants act synergistically in a KCNQ potassium channel binding pocket." in: Nature communications, Vol. 9, Issue 1, pp. 3845, (2018) (PubMed).

Mohamed, Idris, Ahmed, Åstrøm, Mustafa, Ibrahim, Mustafa: "Influence of type 2 diabetes on local production of inflammatory molecules in adults with and without chronic periodontitis: a cross-sectional study." in: BMC oral health, Vol. 15, pp. 86, (2015) (PubMed).
抗原

Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

别名

ANXA1

背景

Background: ANXA1, also known as lipocortin I or Annexin A1, is a protein that in humans is encoded by the ANXA1 gene. It is mapped to 9q21.13. ANXA1 belongs to a family of Ca (2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. ANXA1 protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Lower peptide concentrations possibly found in inflammatory situations elicit Ca (2+) transients without fully activating the mitogen-activated protein kinase pathway. This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge. These findings identified ANXA1 peptides as novel, endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects.
Gene Full Name: annexin A1
Sequence Similarities: Belongs to the annexin family.

分子量

39 kDa

基因ID

301

UniProt

P04083

途径

Hormone Transport