MSH6 抗体 (AA 374-540)
Quick Overview for MSH6 抗体 (AA 374-540) (ABIN6939576)
抗原
See all MSH6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 374-540
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纯化方法
- Purified by Protein A/G
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免疫原
- Recombinant fragment of human MSH6 protein (around aa 374-540) (exact sequence is proprietary)
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亚型
- IgG2b kappa
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anti-MutS Homolog 6 (E. Coli) (MSH6) antibody
MSH6 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7D9H5 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 2E3A10 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 931-1030) antibodyMSH6 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 217-395) antibodyMSH6 适用: 人, 小鼠, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1D1C2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (N-Term) antibodyMSH6 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (Internal Region) antibodyMSH6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) antibodyMSH6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B11 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 1-400) antibodyMSH6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 1-100) antibodyMSH6 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-906R unconjugated Recombinant Antibody
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应用备注
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Positive Control: HCT116, MCF-7 cells, Human colon carcinoma (IHC).
Known Application: ELISA (For coating, order Ab without BSA), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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别名
- MSH6
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背景
- The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2.
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分子量
- 163kDa
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基因ID
- 2956
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UniProt
- P52701
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途径
- DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
抗原
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