ERCC1 抗体 (AA 191-281)
Quick Overview for ERCC1 抗体 (AA 191-281) (ABIN6939333)
抗原
See all ERCC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 191-281
-
特异性
- Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer.
-
纯化方法
- Purified by Protein A/G
-
免疫原
- Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
-
亚型
- IgG2b kappa
-
-
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 151-250) antibody
ERCC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-297) antibodyERCC1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5A2D1 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 151-297) antibodyERCC1 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 1E5B3 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-120) antibodyERCC1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3F9E9 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-323) antibodyERCC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 207-281) antibodyERCC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (Internal Region) antibodyERCC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (Internal Region) antibodyERCC1 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 1-323) antibodyERCC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Excision Repair Cross Complementing Polypeptide-1 (ERCC1) (AA 268-297), (C-Term) antibodyERCC1 适用: 人 WB 宿主: 小鼠 Monoclonal 752CT13-2-5 unconjugated
-
-
应用备注
-
Positive Control: HeLa, HepG2 cells. Tonsil or Prostate.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
-
限制
- 仅限研究用
-
-
-
浓度
- 200 μg/mL
-
缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-80 °C
-
储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
有效期
- 24 months
-
-
- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
-
别名
- ERCC1
-
分子量
- 110kDa
-
基因ID
- 2067
-
UniProt
- P07992
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-
