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ErbB2/Her2 抗体 (Extracellular Domain)

This 小鼠 单克隆 anti-ErbB2/Her2 antibody (Clone HRB2-282) specifically detects ErbB2/Her2 in IF, ELISA, FACS 和 Coat. The antibody is reactive with 人 samples.
产品编号 ABIN6939327
发货至: 中国
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Room 801-803
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Quick Overview for ErbB2/Her2 抗体 (Extracellular Domain) (ABIN6939327)

抗原

See all ErbB2/Her2 抗体
ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

适用

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小鼠

克隆类型

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单克隆

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This ErbB2/Her2 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), ELISA, Flow Cytometry (FACS), Coating (Coat)

克隆位点

HRB2-282
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    Extracellular Domain

    特异性

    Recognizes a protein of 185 kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant extracellular domain of human HER-2 protein

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: SKBR-3 cells. Breast cancer tissue.

    Known Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

    别名

    ERBB2

    分子量

    185kDa

    基因ID

    2064

    UniProt

    P04626

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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