电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

DNMT1 抗体 (AA 767-912)

This anti-DNMT1 antibody is a 小鼠 单克隆 antibody detecting DNMT1 in IHC, ISt 和 StM. Suitable for 人.
产品编号 ABIN6939246
发货至: 中国

Quick Overview for DNMT1 抗体 (AA 767-912) (ABIN6939246)

抗原

See all DNMT1 抗体
DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

适用

  • 188
  • 42
  • 30
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 146
  • 46
  • 1
  • 1
小鼠

克隆类型

  • 133
  • 61
单克隆

标记

  • 87
  • 14
  • 12
  • 10
  • 8
  • 8
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DNMT1 antibody is un-conjugated

应用范围

  • 120
  • 69
  • 60
  • 44
  • 30
  • 28
  • 23
  • 14
  • 14
  • 14
  • 11
  • 10
  • 9
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)

克隆位点

DNMT1-2061
  • 抗原表位

    • 22
    • 21
    • 14
    • 12
    • 11
    • 11
    • 10
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 767-912

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human DNMT1 protein fragment (around aa 767-912) (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Raji cells. Tonsil or Placenta.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

    别名

    DNMT1

    背景

    This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE.

    分子量

    184kDa

    基因ID

    1786

    UniProt

    P26358

    途径

    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
You are here:
Chat with us!