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Decorin 抗体 (AA 212-336)

This anti-Decorin antibody is a 小鼠 单克隆 antibody detecting Decorin in IHC 和 StM. Suitable for 人.
产品编号 ABIN6939230
发货至: 中国

Quick Overview for Decorin 抗体 (AA 212-336) (ABIN6939230)

抗原

See all Decorin (DCN) 抗体
Decorin (DCN)

适用

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宿主

  • 72
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小鼠

克隆类型

  • 77
  • 27
单克隆

标记

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This Decorin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

DCN-3523
  • 抗原表位

    • 13
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    AA 212-336

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human Decorin protein fragment (aa212-336) (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Human prostate or skin tissue (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Decorin (DCN)

    别名

    DCN

    背景

    Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF and is a direct or indirect negative modulator of TGF synthesis. Inhibition of Decorin core protein gene expression by the combination of IFN- and TNF may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. The human Decorin gene maps to chromosome 12q21.33 and encodes a 359 amino acid protein.

    分子量

    43kDa

    基因ID

    1634

    UniProt

    P07585

    途径

    Glycosaminoglycan Metabolic Process
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