BTLA 抗体
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- 抗原 See all BTLA 抗体
- BTLA (B and T Lymphocyte Associated (BTLA))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BTLA antibody is un-conjugated
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应用范围
- ELISA, Coating (Coat)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant full-length human BTLA protein
- 克隆位点
- BTLA-1528
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product BTLA Primary Antibody
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- 应用备注
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Positive Control: Human lymph node or MDAMB468 xenograft.
Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- BTLA (B and T Lymphocyte Associated (BTLA))
- 别名
- BTLA (BTLA 产品)
- 别名
- BTLA antibody, BTLA1 antibody, CD272 antibody, A630002H24 antibody, B and T lymphocyte associated antibody, BTLA antibody, Btla antibody
- 背景
- B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are coinhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between Mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.
- 分子量
- 33kDa
- 基因ID
- 151888
- 途径
- Cancer Immune Checkpoints
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