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BTLA 抗体

This 小鼠 单克隆 anti-BTLA antibody (Clone BTLA-1528) specifically detects BTLA in ELISA 和 Coat. The antibody is reactive with 人 samples.
产品编号 ABIN6939222
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BTLA 抗体 (ABIN6939222)

抗原

See all BTLA 抗体
BTLA (B and T Lymphocyte Associated (BTLA))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This BTLA antibody is un-conjugated

应用范围

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ELISA, Coating (Coat)

克隆位点

BTLA-1528
  • 纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant full-length human BTLA protein

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: Human lymph node or MDAMB468 xenograft.

    Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    BTLA (B and T Lymphocyte Associated (BTLA))

    别名

    BTLA

    背景

    B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are coinhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between Mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.

    分子量

    33kDa

    基因ID

    151888

    途径

    Cancer Immune Checkpoints
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