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- 抗原 See all CTNND1 抗体
- CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CTNND1 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Mouse p120 Catenin (pY96)
- 克隆位点
- 25a
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CTNND1 Primary Antibody
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anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 573-832) antibody
CTNND1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibodyCTNND1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 841-890) antibodyCTNND1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (Tyr228) antibodyCTNND1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 482-605) antibodyCTNND1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) antibodyCTNND1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (pTyr228) antibodyCTNND1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (pTyr228) antibodyCTNND1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (AA 1-610) antibodyCTNND1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (N-Term) antibodyCTNND1 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, Pig, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: HeLa cells. HeLa whole cell lysate.
Known Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- CTNND1 (Catenin (Cadherin-Associated Protein), delta 1 (CTNND1))
- 别名
- CTNND1 (CTNND1 产品)
- 别名
- CAS antibody, CTNND antibody, P120CAS antibody, P120CTN antibody, p120 antibody, p120(CAS) antibody, p120(CTN) antibody, Catns antibody, cas antibody, Xp120 antibody, ctnnd antibody, p120cas antibody, p120ctn antibody, p120(ctn) antibody, Xp120(ctn) antibody, p120-catenin antibody, CTNND1 antibody, AA409437 antibody, AU019353 antibody, Ctnnd antibody, P120 antibody, mKIAA0384 antibody, catenin delta 1 antibody, catenin (cadherin-associated protein), delta 1 antibody, catenin (cadherin associated protein), delta 1 antibody, catenin delta 1 L homeolog antibody, CTNND1 antibody, Ctnnd1 antibody, ctnnd1 antibody, ctnnd1.L antibody
- 背景
- The membrane associated protein pp120 Src substrate (p120 Catenin, p120cas) was identified as a tyrosine kinase substrate that is phosphorylated in Src transformed cells or in response to growth factor stimulation. It shares structural similarity with the Drosophila Armadillo protein and the vertebrate beta-catenin and gamma-catenin proteins. Its characteristic Arm domain that is composed of 42-amino acid motif repeats evidences this similarity. In the cell, p120 Catenin is localized to the E-Cadherin/catenins cell adhesion complex. Like beta- and gamma-catenin, p120 Catenin directly associates with the cytoplasmic C-terminus of E-Cadherin via its Arm domain and may similarly interact with other Cadherins. It exists as four isoforms that range in size from 90-115 kDa. Expression of these isoforms is heterogeneous in human carcinomas, suggesting that altered pp120 expression contributes to malignancy due to loss of functional cell adhesions. Multiple tyrosine residues (Y96, Y112, Y228, Y280, Y257, Y291, Y296, and Y302) in p120 Catenin are phosphorylated by Src and these phosphorylations may facilitate interaction with PTP1C/SHP-1 in response to EGF stimulation. Thus, p120 Catenin is an Arm domain protein that interacts with both cell adhesion molecules, such as cadherins and cell signaling molecules, such as PTP1C.
- 分子量
- 120kDa
- 基因ID
- 1500
- UniProt
- O60716
- 途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
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