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CTNNB1 抗体 (C-Term)

Name: CTNNB1 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN6939205
Availability: OutOfStock

This anti-CTNNB1 antibody is a 小鼠单克隆 antibody detecting CTNNB1 in WB, IHC, IF, FACS 和 StM. Suitable for 人, 小鼠和小鸡.

Western Blot of A431 and A549 cell lysates using Catenin, beta Mouse Monoclonal Antibody (5H10) (CTNNB1 抗体 (C-Term))

Flow Cytometric Analysis of PFA fixed HeLa cells using Beta-Catenin (p120) Monoclonal Antibody (5H10) followed by goat anti-mouse IgG-CF488 (Blue), Isotype Control (Red). (CTNNB1 抗体 (C-Term))

FACS

Formalin-fixed, paraffin-embedded human Tonsil stained with Beta-Catenin (p120) Monoclonal Antibody (5H10). (CTNNB1 抗体 (C-Term))

IHC

SDS-PAGE Analysis of Purified Beta-Catenin (p120) Monoclonal Antibody (5H10). (CTNNB1 抗体 (C-Term))

SDS

4 images

产品编号 ABIN6939205

发货至: 中国

Quick Overview for CTNNB1 抗体 (C-Term) (ABIN6939205)

抗原

See all CTNNB1 抗体

CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

适用

人, 小鼠, 小鸡

宿主

小鼠

克隆类型

单克隆

标记

This CTNNB1 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)

克隆位点

5H10

Discover our top product CTNNB1 Primary Antibody

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C-Term

纯化方法

Purified by Protein A/G

免疫原

Fusion protein consisting of the maltose binding protein fused to a 100 amino acid segment of the C-terminus of chicken beta-Catenin

亚型

IgG1 kappa
anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (N-Term) antibody
KO Validated CTNNB1 适用: 人 WB, IHC, IF, FACS, IHC (p), IP, ICC, IHC (fro), ChIP, CUT&RUN, IHC (wm) 宿主: 兔 Polyclonal unconjugated

anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (N-Term) antibody
CTNNB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 2-781) antibody
CTNNB1 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (AA 682-781) antibody
CTNNB1 适用: 人 WB, ELISA, IF, PLA, RNAi 宿主: 小鼠 Monoclonal 1C9 unconjugated

anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody
CTNNB1 适用: 人 WB, IHC, IF, FACS, StM 宿主: 兔 Monoclonal CTNNB1-2030R unconjugated Recombinant Antibody

anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody
CTNNB1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 9C1 unconjugated

anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody
CTNNB1 适用: 人, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 6A3 unconjugated

anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody
CTNNB1 适用: 人, 大鼠, 犬, 猴 WB, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal 9H2 unconjugated

anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody
CTNNB1 适用: 人, 大鼠, 猴 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 12H7 unconjugated

anti-Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) antibody
CTNNB1 适用: 人, 犬 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1E10 unconjugated

应用备注

Positive Control: A431 or A549 cells. Breast carcinoma or Tonsil.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

限制

仅限研究用
浓度

200 μg/mL

缓冲液

10 mM PBS with 0.05 % BSA & 0.05 % azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-80 °C

储存方法

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

有效期

24 months
抗原

CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))

别名

CTNNB1

背景

Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, beta-catenin is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution of beta-catenin throughout the cytoplasm results in a diffuse cytoplasmic pattern. Immuno-staining of beta-catenin and E-cadherin is helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic beta-catenin staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas.

分子量

92kDa

基因ID

1499

UniProt

P35222

途径

WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2