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Recombinant CD21 抗体 (AA 44-196)

This anti-CD21 antibody is a 小鼠 单克隆 antibody detecting CD21 in IHC 和 StM. Suitable for 人.
产品编号 ABIN6939181
发货至: 中国

Quick Overview for Recombinant CD21 抗体 (AA 44-196) (ABIN6939181)

抗原

See all CD21 (CR2) 抗体
CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD21 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

RCR2-1952
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    AA 44-196

    特异性

    Recognizes a protein of 140 kDa, which is identified as the complement receptor 2(CR2)/CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro.CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha.CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment (around aa 44-196) of human CR2 (CD21) protein (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: WEHI-231 cells. Human tonsil (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD21 (CR2) (Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2))

    别名

    CR2

    分子量

    140kDa

    基因ID

    1380

    UniProt

    P20023

    途径

    Complement System
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