Recombinant MALT1 抗体 (AA 701-808)
Quick Overview for Recombinant MALT1 抗体 (AA 701-808) (ABIN6939112)
抗原
See all MALT1 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 701-808
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特异性
- Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11,18)(q21,q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
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交叉反应 （详细）
- Human,
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa701-808) of human MALT1 protein (exact sequence is proprietary)
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亚型
- IgG1
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anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 125-450) antibody
MALT1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 WB, IHC (f) 宿主: 小鼠 Monoclonal MT1-410 unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (Internal Region) antibodyMALT1 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 701-808) antibodyMALT1 适用: 人 IHC (f) 宿主: 兔 Monoclonal MT1-3159R unconjugated Recombinant Antibody
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 685-784) antibodyMALT1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1) (AA 1-813) antibodyMALT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Positive Control: Jurkat, Daudi or HeLa cells. Tonsil or lymphoma.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
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有效期
- 24 months
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- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
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别名
- MALT1
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背景
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Caspase-like protein, MALT lymphoma-associated translocation, MLT1, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Paracaspase,MALT1 (MALT-Lymphoma Marker)
Cellular localisation: Cytoplasmic -
分子量
- 93kDa
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基因ID
- 10892, 601217
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UniProt
- Q9UDY8
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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