BAFF 抗体
Quick Overview for BAFF 抗体 (ABIN6939086)
抗原
See all BAFF (TNFSF13B) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN- BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).
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交叉反应 (详细)
- Human,
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纯化方法
- 200ug/ml of Ab Purified from rabbit anti-serum by Protein A.
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免疫原
- Purified recombinant human CD257 protein
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亚型
- IgG1
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应用备注
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Positive Control: Jurkat cells. Tonsil and lymph node.
Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
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有效期
- 24 months
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- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
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别名
- TNFSF13B
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背景
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ApoL related ligand TALL 1, B lymphocyte stimulator, B-cell-activating factor, BAFF, BLyS, CD257, Dendritic cell-derived TNF-like molecule, DTL, PRO738, TALL-1, THANK, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13b, Tumor necrosis factor ligand superfamily member 20, ZTNF4,CD257 / BAFF / TNFSF13B
Cellular localisation: Cell surface and cytoplasmic -
分子量
- 31kDa (Monomer)
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基因ID
- 10673, 525157
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UniProt
- Q9Y275
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
抗原
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