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Uroplakin 1B 抗体 (AA 109-229)

This 小鼠 单克隆 anti-Uroplakin 1B antibody (Clone UPK1B-3081) specifically detects Uroplakin 1B in ELISA, Coat 和 IHC (f). The antibody is reactive with 人 samples.
产品编号 ABIN6938732
发货至: 中国
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Quick Overview for Uroplakin 1B 抗体 (AA 109-229) (ABIN6938732)

抗原

See all Uroplakin 1B (UPK1B) 抗体
Uroplakin 1B (UPK1B)

适用

  • 43
  • 4
  • 3

宿主

  • 24
  • 19
小鼠

克隆类型

  • 24
  • 19
单克隆

标记

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  • 2
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This Uroplakin 1B antibody is un-conjugated

应用范围

  • 26
  • 18
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ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

UPK1B-3081
  • 抗原表位

    • 22
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
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    • 1
    AA 109-229

    特异性

    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.UPK1B is expressed by terminally differentiated urothelial cells.

    交叉反应 (详细)

    Human.

    纯化方法

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    免疫原

    Recombinant fragment (around aa 109-229) of human Uroplakin 1B (UPK1B) protein (exact sequence is proprietary)

    亚型

    IgG2b kappa
  • 应用备注

    Known_Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Urinary Bladder.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    有效期

    24 months
  • 抗原

    Uroplakin 1B (UPK1B)

    别名

    UPK1B

    背景

    Tetraspanin-20, Tspan-20, TSPAN20, UP1b, UPIb, UPK1B, Uroplakin-1b,Uroplakin 1B (Urothelial Differentiation Marker)
    Cellular localisation: Cell Surface

    分子量

    30kDa

    基因ID

    7348, 271580

    UniProt

    O75841
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